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Simon has been at the University of Bath since 2008. His research is in synthetic chemistry. He is the recipient of scholarships from Syngenta (then Zeneca) and Pfizer and was jointly awarded the Neil Arnott Prize for the best graduating chemist of all colleges in the University of London. In 2013, he was awarded the University of Bath John Willis Award for dedication to the academic and personal lives of students combined with a significant contribution to teaching and accomplishment in research.